王慧枝
  • 文章来源:生物医学工程
  • 阅读次数:3743
  • 2024-10-11

王慧枝,中国科学技术大学苏州高等研究院特任副研究员,硕士生导师。主要研究方向为骨肌系统生物力学、植入物设计、穿戴式数字诊疗装备。已在Advanced Science, Bone & Joint Research, Journal of Orthopaedic Translation, Measurement, Knee Surgery Sports Traumatology Arthroscopy等国际学术期刊上发表相关论文34篇,申请/授权国家专利9项,获姑苏创新领军人才计划项目、国自然青年科学基金项目、江苏省自然科学基金面上项目、上海市“超级博士后”激励计划、中国博士后面上项目等资助。担任SCI期刊Bioengineering-Basel编委。


工作经历

2023/06-至今,中国科学技术大学苏州高等研究院,特任副研究员

2020/06-2023/06,上海交通大学生物医学工程学院,博士后

2016/08-2017/08,美国匹兹堡大学骨肌研究中心,Pre-doctoral fellow

学习经历

2015/09-2020/06,北京航空航天大学生物与医学工程学院,博士

2014/09-2015/06,北京航空航天大学生物与医学工程学院,硕士

2010/09-2014/06,首都医科大学生物医学工程学院,学士

电子邮箱

wang_huizhi8866@163.com;  wang_huizhi8866@ustc.edu.cn

主要科研项目

1. 江苏省自然科学基金面上项目: “前交叉韧带(ACL)重建术中移植体刚度个性化选择的生物力学研究”, 2025.07-2028.06, 主持, 项目批准号: BK20251817.

2. 姑苏创新领军人才计划项目: “穿戴式肌肉力动态监测系统的研发”, 2024.12-2027.12, 主持, 项目批准号: ZXL2024352.

3. 国自然青年科学基金项目: “前交叉韧带-骨界面宏微观形态及其对界面力传导的影响”, 2022.01-2024.12, 主持, 项目批准号: 32101050.

4. 上海市“超级博士后”激励计划项目: “ACL 骨止点解剖生物力学的定量化评估及其仿生支架的设计”, 2022.01-2023.12, 主持, 项目批准号: 2020262.

5. 中国博士后科学基金面上项目: “前交叉韧带-骨界面超微观形态及力学属性对其力传导特点的影响机制”, 2022.01-2024.12, 主持, 项目批准号: 2021M702129.

6. 北京市自然科学基金项目: “无托槽隐形矫治器在体实时测力关键技术研究及系统开发”, 2023.11-2026.12, 参与, 项目批准号: L232108, 主持单位:北京大学口腔医院.

获奖及荣誉情况

1. 2024: 姑苏创新领军人才

2. 2020: 2020年度上海市“超级博士后”激励计划

3. 2020: 2020年度研究生发表优秀学术论文奖

4. 2014: 北京市优秀毕业生(市级,北京市,全院共1名)

5. 2013: 北京市三好学生(市级,北京市,全院共1名)

6. 2013: 一等奖学金(校级,首都医科大学,全院共2名)

7. 2012: 北京市三好学生(市级,北京市,全院共1名) 

8. 2012: 一等奖学金(校级,首都医科大学,全院共2名)

9. 2011: 第二十八届全国部分地区大学生物理竞赛B类二等奖(国家级,中国)

主要学术论文

1. Sun R, Wang J, Wang Z, Nie Y*, Wang H*, Pan T*. (2026) Biomechanics-Informed Machine Learning for Accurate Estimation of Single-Foot 3D Ground Reaction Forces Using a Fully Wearable System. Measurement, 264:120165.

2. Li Y, Ji X, Yang Q, Wang H*, Cheng C-K*. (2026) The Role of the Deltoid Ligament in Multidirectional Stability and Articular Stress of the Ankle Joint: A Finite Element Analysis. Bioengineering-Basel, Accepted.

3. Wang Z, Fang C, Sun R, Feng C, Wang X, Bi H, Wu Y, Gong J, Wang Y, Guo J, Chang Y*, Wang H*, Pan T*. (2025) A Wearable System Featuring Biomimetic Spatially Distributed Iontronic Sensing Array for Dynamic Monitoring of Deep Tissue Modulus. Advanced Science, e19009.

4. Wang H, Yang Q, Shi Q, He K, Feng W, Li L, Cheng C-K*. (2025) Spatially Resolved Structure-Function Mapping of the ACLBone Interface: Regional Variation in Microarchitecture, Tensile Properties, and Stress Distribution. Bone & Joint Research, 14(11):1006-1015.

5. He K, Yang Q, Shi Q, Wang H*, Cheng C-K*. (2025) Variation in Area Proportion and Mechanical Properties Between Different Subregions of ACL Insertion: An In Vitro Biomechanical Study in a Porcine Model. Journal of Experimental Orthopaedics, 12:e70470.

6. Wang H, Yao G, He K, Wang Z*, Cheng C-K*. (2024) ACL reconstruction combined with anterolateral structure reconstruction for treating ACL rupture and knee injuries: a finite element analysis. Frontiers in Bioengineering and Biotechnology, 12:1437684.

7. Wang H, He K, Cheng C-K*. (2024) The structure, biology and mechanical function of tendon/ligament-bone interfaces. Tissue Engineering. Part B, Reviews, 30(5):545-558.

8. Wang H, Zhang Z, Shi Q, Zeng Y-M, Cheng C-K*. (2023) Correlation between Morphological Features of the Anterior Cruciate Ligament: A Quantitative Study Using a Porcine Model. Frontiers in Veterinary Science, 10:1115068.

9. Wang H, Fang C, Tao M, Shi Q, He K, Cheng CK*. (2022) Hourglass-shaped Grafts Are Superior to Conventional Grafts for Restoring Knee Stability and Graft Force at Knee Flexion Angle of 30° Following Anterior Cruciate Ligament Reconstruction: a finite element analysis. Frontiers in Bioengineering and Biotechnology, 10:967411.

10. Liu B, Wang H, Zhang M, Li JW, Zhang NZ, Luan YC, Fang CH, Cheng CK*. (2022) Capability of auxetic femoral stems to reduce stress shielding after total hip arthroplasty. Journal of Orthopaedic Translation, 38(5):220-228.

11. Shi Q, Wang H*, He K, Tao M, Cheng C-K*. (2022) Comparison of the morphology of the anterior cruciate ligament and related bony structures between pigs and humans. Frontiers in Veterinary Science, 9:1045785.

12. Wang H, Tao M, Shi Q, He K, Cheng C-K*. (2022) Graft Diameter Should Reflect the Size of the Native Anterior Cruciate Ligament (ACL) to Improve the Outcome of ACL Reconstruction: A Finite Element Analysis. Bioengineering-Basel, 9(10), 507.

13. Cheng R#, Wang H#, Dimitriou D, Jiang Z, Cheng C-K*, Tsai T-Y*. (2022) Central femoral tunnel placement can reduce stress and strain around bone tunnels and graft more than anteromedial femoral tunnel in anterior cruciate ligament reconstruction. International Journal For Numerical Methods In Biomedical Engineering, e3590.

14. Wang H, Zhang Z, Qu Y, Shi Q, Ai S*, Cheng C-K*. (2022) Correlation between ACL size and dimensions of bony structures in the knee joint. Annals of Anatomy-Anatomischer Anzeiger, 241:151906.

15. Cheng R#, Wang H#, Jiang Z, Dimitriou D, Cheng C-K*, Tsai T-Y*. (2021) The femoral tunnel drilling angle at 45° coronal and 45° sagittal provided the lowest peak stress and strain on the bone tunnels and anterior cruciate ligament graft. Frontiers in Bioengineering and Biotechnology, 9:797389.

16. Wang H, Zhang M, Cheng CK*. (2020) Changing the diameter of the bone tunnel is more effective than changing the tunnel shape for restoring joint functionality after ACL reconstruction. Frontiers in Bioengineering and Biotechnology, 8:173.

17. Wang H, Zhang M, Cheng C-K*. (2020) A novel protection liner to improve graft-tunnel interaction following anterior cruciate ligament reconstruction: a finite element analysis. Journal of Orthopaedic Surgery and Research, 15(1):1-10.

18. Wang H, Zhang B, Cheng C-K*. (2020) Stiffness and shape of the ACL graft affects tunnel enlargement and graft wear. Knee Surgery Sports Traumatology Arthroscopy, 28(7):2184-2193.

19. Wang H, Kang H, Yao J, Cheng C-K*, Woo SL-Y*. (2019) Evaluation of a magnesium ring device for mechanical augmentation of a ruptured ACL: Finite element analysis. Clinical Biomechanics, 68:122-127.

专利发明

1. Pan T, Wang H, Chang Y, Wang Z. “Wearable device, system, and method for monitoring soft-tissue Youngs modulus” (US 19/299,377), Suzhou Institute for Advanced Research, University of Science and Technology of China, Suzhou, CHINA; University of Science and Technology of China, Hefei, CHINA, 2025/08/14, under examination.

2. Pan T, Wang H, Chang Y, Wang Z. “Wearable device for monitoring soft-tissue Youngs modulus”, (US 19/299,385), Suzhou Institute for Advanced Research, University of Science and Technology of China, Suzhou, CHINA; University of Science and Technology of China, Hefei, CHINA, 2025/08/14, under examination.

3. 杨晴晴, 王慧枝, 郑诚功. “一种带间接止点的移植韧带及植入方法” (202511506792.4), 上海交通大学, 2025/10/21. (发明专利,已进入实质审查)

4. 潘挺睿, 王慧枝, 常煜, 王振宁. “可穿戴软组织杨氏模量监测装置、系统及方法” (CN202411814270.6), 中国科学技术大学苏州高等研究院, 中国科学技术大学, 2024/12/11. (发明专利,已进入实质审查)

5. 潘挺睿, 王慧枝, 常煜, 王振宁. “可穿戴软组织杨氏模量监测装置” (202423047131.3), 中国科学技术大学苏州高等研究院, 中国科学技术大学, 2026/01/04. (实用新型专利,已授权)

6. 王慧枝, 郑诚功, “一种韧带移植物固定装置” (CN 116211538 B), 上海交通大学, 2025/06/24. (发明专利,已授权)

7. 郑诚功, 聂茂丹,王慧枝. “一种新型韧带重建系统” (CN 217138354 U), 上海交通大学, 2022/08/09. (实用新型专利,已授权)

8. 王慧枝, 郑诚功, “喇叭状植入物” (CN 209301404 U) 北京航空航天大学,2019/08/27. (实用新型专利,已授权)

9. 王慧枝, 郑诚功, “喇叭状植入物及其植入方法” (CN 109567983 B) 北京航空航天大学,2020/12/22. (发明专利,已授权)


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