邓正玉
  • 文章来源:生物医学工程
  • 阅读次数:35
  • 2024-10-13


邓正,中国科学技术大学生物医学工程学院、化学与材料科学学院特任研究员,入选中科院人才计划青年项目。主要从事智能高分子生物材料的研究,即利用新的化学设计开发新型智能高分子材料,并应用于生物医学研究。迄今已在Nat. Chem., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Prog. Polym. Sci., JACS Au, ACS Mater. Lett.等国际国内学术期刊上发表SCI论文30篇,已发表的论文共被引1400余次,H因子20。任多个专业领域期刊 (包括Macromolecules, Biomacromolecules) 的独立审稿人。作为主要发明人获授权多项发明专利。

个人主页:https://zydeng1990.wixsite.com/deng-research-group

 

工作经历: 

2024/07-至今,中国科学技术大学苏州高等研究院,特任研究员

2021/3-2024/06,加拿大西安大略大学 (University of Western Ontario),博士后,导师:Elizabeth R. Gillies

2017/6-2019/09,湖南大学,博士后,导师:谭蔚泓院士

学习经历  

2011/09-2017/03,中国科学技术大学高分子科学与工程系,博士,导师:刘世勇教授

2007/09-2011/06,西北工业大学应用化学系,学士

电子邮箱

zydeng@ustc.edu.cn

招生招聘信息

实验室招研究生、博士后、副研究员。有化学、材料学以及生物学背景均可同通过邮件联系。诚挚欢迎对本实验室研究方向感兴趣的优秀人才加盟,共同进步。

主要科研项目

中国科学技术大学高层次人才引进计划启动经费,2024-2027,主持

主要研究方向

智能生物材料,精密高分子,生物正交化学

代表论文 

1. Cen, J.#; Liu, W.#; Xu, J.#; Wang, X.; Zhang, J.; Zhang, J.; Deng, Z.*; Zhou, C.*; Hu, J.*; Liu, S.* Single-Component High-Resolution Dual-Tone EUV Photoresists Based on Precision Self-Immolative Polymers, Angew. Chem. Int. Ed.2024, 63, e202415588.

2. Deng, Z.; Liang, X.; Gillies, E. R.* Click to Self-immolation: A “Click” Functionalization Strategy towards Triggerable Self-Immolative Homopolymers and Block Copolymers, Angew. Chem. Int. Ed.2024, 63, e202317063 (Hot Paper).

3. Tan, J.#; Deng, Z.#; Song, C.; Xu J.; Zhang, Y.; Yu, Y.; Hu, J.*; Liu, S.* Coordinating External and Built-In Triggers for Tunable Degradation of Polymeric Nanoparticles via Cycle Amplification, J. Am. Chem. Soc.2021, 143, 13738.

4. Yang, Q.#; Deng, Z.#; Wang, D.; He, J.; Zhang, D.; Tan, Y.; Peng, T.; Wang, X. Q.*; Tan, W.* Conjugating Aptamer and Mitomycin C with Reductant-Responsive Linker Leading to Synergistically Enhanced Anticancer Effect, J. Am. Chem. Soc.2020, 142, 2532.

5. Deng, Z.; Yuan, S.; Xu, X. R.; Liang, H.; Liu, S.* Reduction-Triggered Transformation of Disulfide-Containing Micelles at Chemically Tunable Rates, Angew. Chem. Int. Ed.2018, 57, 8896.

6. Deng, Z.; Qian, Y.; Yu, Y.; Liu, G.; Hu, J.; Zhang, G.; Liu, S.* Engineering Intracellular Delivery Nanocarriers and Nanoreactors from Oxidation-Responsive Polymersomes via Synchronized Bilayer Cross-Linking and Permeabilizing Inside Live Cells, J. Am. Chem. Soc.2016, 138, 10452 (ESI Highly Cited Papers).

7.  Deng, Z.; Gillies, E. R.* Emerging Trends in the Chemistry of End-to-End Depolymerization, JACS Au2023, 3, 2436.

8. Shi, Q.#; Deng, Z.#; Hou, M.#; Hu X.*; Liu S.* Engineering precise sequence-defined polymers for advanced functions, Prog. Polym. Sci.2023, 141, 101677.

9. Deng, Z.; Shi, Q.; Tan, J.; Hu, J.*; Liu, S.* Sequence-Defined Synthetic Polymers for New-Generation Functional Biomaterials, ACS Mater. Lett.2021, 3, 1339.

10. Deng, Z.; Liu, S.* Controlled drug delivery with nanoassemblies of redox-responsive prodrug and polyprodrug amphiphiles,J. Controlled Release 2020, 326, 276.

  







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