杨文
  • 文章来源:生物医学工程
  • 阅读次数:899
  • 2023-05-09


杨文,中国科学技术大学苏州高等研究院特任副研究员,主要从事等离激元生物传感器及纳米生物技术研究:围绕纳米颗粒和微流控系统,开发集成光流体等离激元生物传感平台,实现生物标记物从全血到单细胞水平的高灵敏度、快速、多参数检测,用于早期疾病筛查和诊断。目前发表 SCI 期刊论文 10 篇,国际会议论文 1 篇,专利 2 篇。担任多个期刊审稿人、客座编辑等。

工作经历

2022/03-至今,中国科大苏州高等研究院,特任副研究员

2015/09-2016/6,厦门大学,科研助理,导师:谢水奋

学习经历

2016/08-2022/08,美国Auburn University,材料学院,博士,导师:Pengyu Chen

2011/09-2015/06,华侨大学,高分子材料与工程,学士

电子邮箱

imedyangwen@ustc.edu.cn

主要科研项目

1.等离激元生物传感器用于高时空分辨单细胞分泌成像及细胞通讯成像;

2.细胞免疫分析;

3.单分子检测及数字ELISA

主要学术论文

1.C. Wang, C. Huang, Z. Gao, J. Shen, J. He, A. MacLachlan, C. Ma, Y. Chang, W. Yang, Y. Cai, Y. Lou, S. Dai, W. Chen, F. Li, and P. Chen, "Nanoplasmonic Sandwich Immunoassay for Tumor-Derived Exosome Detection and Exosomal PD-L1 Profiling". ACS sensors, 6(2021): 3308-3319.

2.X.Kang, Y. Cai, Q. Wang, C. Wang, W. Chen, W. Yang, A. Suryawanshi, G. Zhou, P. Chen, and F. Li*, "Near-infrared light triggered activation of pro-drug combination cancer therapy and induction of immunogenic cell death", International Journal of Pharmaceutics, 607 (2021): 120972.

3.P. Chen, F. Ding, R. Cai, I. Javed, W. Yang, Z. Zhang, Y. Li, T. P. Davis, P. C. Ke*, and C. Chen*, "Amyloidosis Inhibition, a New Frontier of the Protein Corona," Nano Today, 35 (2020): 100937.

4.W. Yang, H. Veroniaina, X. Qi*, P. Chen*, F. Li*, P. C. Ke, "Soft and Condensed Nanoparticles and Nanoformulations for Cancer Drug Delivery and Repurpose," Advanced Therapeutics, 3 (2020):1900102.

5.Faridi, W. Yang, H. G. Kelly, C. Wang, T. P. Davis*, P. Chen*, S. J. Kent*, P. C. Ke*, "Differential Roles of Plasma Protein Corona on Immune Cell Association and Cytokine Secretion of Oligomeric and Fibrillar Beta-Amyloid," Biomacromolecules, 20 (2019): 4208.

6.Y. Chang, J. Jiang, W. Chen, W. Yang, L. Chen, P. Chen, J. Shen, S. Qian, T. Zhou, L. Wu, L. Hong, Y. Huang*, F. Li*. "Biomimetic metal-organic nanoparticles prepared with a 3D-printed microfluidic device as a novel formulation for disulfiram-based therapy against breast cancer," Applied materials today, 18 (2020): 100492.

7.I. Javed, J. He, A. Kakinen, A. Faridi, W. Yang, T. P. Davis*, P. C. Ke*, and P. Chen*, "Probing the Aggregation and Immune Response of Human Islet Amyloid Polypeptide with Ligand-Stabilized Gold Nanoparticles," ACS Appl. Mater. Interfaces, 11 (2019): 10462.

8.Y. Cai, J. Zhu, J. He, W. Yang, C. Ma, F. Xiong, F. Li, W. Chen, and P. Chen*, "Magnet Patterned Superparamagnetic Fe3O4/Au Core–Shell Nanoplasmonic Sensing Array for Label‐Free High Throughput Cytokine Immunoassay, " Advanced healthcare materials, 8(2019): 1801478.

9.W. Chen, W. Yang, P. Chen, Y. Huang, and F. Li*, "Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers," ACS Appl. Mater. Interfaces, 10 (2018): 41118.

10.X. W. Ge, A. Kakinen, E. N. Gurzov, W. Yang, L. Pang, E. H. Pilkington, P. Nedumpully-Govindan, P. Chen, F. Separovic, T. P. Davis*, P. C. Ke*, F. Ding*, "Zinc-Coordination and C-Peptide Complexation: A Mechanism for the Native Inhibition of IAPP Aggregation," Chem. Comm, 53 (2017): 9394.

11.W. Yang, J. He, and Pengyu Chen. "Nanoplasmonic cytokine biosensor towards precision medicine." In 2016 10th International Conference on Sensing Technology (ICST), pp. 1-4. IEEE, 2016.

12.S. Wang, W. Yang, G. H. Chen*. "Graphene-decorated porous ceramics for efficient removal of Cr (VI), "RSC Advances, 5 (2015): 65982-65990.

专利发明

1.谢水奋,王伟,许清池,杨文. “一种铑碲合金空心纳米管的制备方法”,中国发明专利,CN106975756A

2.陈国华,王师,杨文. “石墨烯-多孔陶瓷复合吸附材料及其制备方法与应用”, 中国发明专利, CN104475019A



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